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Multiple functions of IRF-8 in the immune system. Roles for IRF-8 in both the myeloid (blue box) and lymphoid (orange box) arms of the immune system can be stratified into 3 basic tiers reflecting 3 fundamental cellular processes: development (pink), function (green), and oncogenic potential (purple). IRF-8 either suppresses (red line) or supports (green lines) the various cell types and their activities, as indicated.
