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. 2016 Jul;358(1):109–124. doi: 10.1124/jpet.116.232728

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Fig. 8. — Effects of presession treatments with novel σR ligands (SN 167, CM 353, CM 398, and (±)-SM 21) on responding maintained by (+)-pentazocine, PRE-084, or DTG injection. Each point represents the mean ± S.E.M. (n = 6). Ordinates are responses per second. Abscissae are the injection dose in milligrams per kilogram (i.p.). Closed circles represent rates of responding maintained by the σR agonists when vehicle was injected 5 minutes before the experimental session. Open symbols represent rates of responding maintained by cocaine when SN 167, CM 353, CM 398, or (±)-SM 21 at doses specified in the key were injected 5 minutes before the experimental session.