TABLE 2.
Most upregulated genes in MEFs expressing Hnf1a and Hnf4a are enriched in the proximal tubule compared with liver
| Gene Symbol | Category | Hnf1a + Hnf4a versus Uninfected (Fold Change) | E15.5 PT versus E 15.5 Liver (Ratio) | Adult PT versus Adult Liver (Ratio) |
|---|---|---|---|---|
| Slc22a6 (Oat1) | Transporter | 3439 | 10.3 | 19.4 |
| Slc34a1 (Npt2a) | Transporter | 1337 | 37.9 | 337.5 |
| Abcc2 (Mrp2) | Transporter | 1192 | 0.9 | 1.2 |
| Cldn6 (Claudin 6) | Junction | 895 | 7.2 | 1.0 |
| Slc51b (Ostb) | Transporter | 715 | 4.6 | 4.1 |
| Slc22a12 (Urat1) | Transporter | 576 | 4.8 | 16.3 |
| Slco1a6 (Oatp1a6) | Transporter | 347 | 115.4 | 118.3 |
| Slc47a1 (Mate1) | Transporter | 195 | 12.3 | 2.8 |