Fig. 2.

Correlation relationships (Spearman’s correlation; α = 0.05) in relative gene expression (triplicate determinations of molecule number per sample, normalized to GAPDH, and log₂-transformed) between (A) PXR and VIL1 across all tissue samples (n = 30; r = 0.78, P = 0.01); (B) PXR and IL8 in the TI of CD (r = –0.45, P = 0.06) and controls (r = 0.18, P = 0.6), (C) VIL1 and IL8 in the TI of CD (r = –0.44, P = 0.07) and controls (r = 0.27, P = 0.4), and (D) CYP3A4 and IL8 in the TI of CD (r = –0.68, P < 0.01) and controls (r = 0.21, P = 0.5). Crohn’s disease (CD) tissue denoted by cross (n = 18), control tissue by circle (n = 12).