Fig. 6.

Differences in CYP3A7 promoter occupancy by modified and variant histones or transcription factors between pooled fetal (N = 14) and pooled postnatal (N = 10) hepatic chromatin were evaluated using a Mann-Whitney U test. The data are shown as red- or green-tinted heat maps (see legend) of the P value ranges. Red and green tints indicate greater occupancy in the postnatal and fetal chromatin, respectively. Yellow indicates no significant difference (NS). N/A, not assayed. Modified and variant histones are grouped into those associated with active (green font), poised (blue font), or inactive transcription (red font). The relevant occupancy by transcription factors (black font) is also shown.