Table 2. Univariate and multivariate analyses of the association of prognosis with clinicopathologic parameters and miR-203 expression in CRC patients.
| Variable | Univariable analysis |
Multivariable analysis |
||||
|---|---|---|---|---|---|---|
| HR (95% CI) | P-value | HR (95% CI) | P-value | |||
| Age (<50/≥50) | 0.741 (0.368–1.275) | 0.362 | – | – | ||
| Gender (male/female) | 1.308 (0.694–2.147) | 0.618 | – | – | ||
| Differentiation (well/moderately, poorly) | 1.324 (0.780–2.409) | 0.356 | – | – | ||
| Tumor size (<5 cm/≥5 cm) | 1.182 (0.836–1.582) | 0.367 | – | – | ||
| Tumor location (Colon/Rectum) | 0.946 (0.703–1.422) | 0.306 | – | – | ||
| Lymph node metastasis (present/absent) | 6.545 (3.184–11.608) | <0.001 | 4.234 (3.104–8.332) | 0.03 | ||
| TNM stage (AJCC) (I-II/III-IV) | 5.501 (2.243–13.462) | <0.001 | 5.043 (2.417–9.455) | 0.007 | ||
| miR-203 expression (high/low) | 2.687 (1.204–5.764) | 0.003 | 1.725 (1.139–3.053) | 0.016 | ||
Bold values indicate statistical significance, P < 0.05, CI, confidence interval; HR, hazard ratio.