Table 3.

Distribution of Allele Frequencies for Controls and Crohn’s Disease Subjects in Discovery Cohort

SNP	Controls MAF	CD MAF	Odds ratio	95% CI	P Value
rs4810424	0.152	0.202	1.407	1.099 – 1.800	0.007*
rs1884613	0.148	0.200	1.432	1.118 – 1.835	0.004*
rs1884614	0.149	0.201	1.429	1.116 – 1.829	0.005*
rs6031543	0.147	0.148	1.000	0.758 – 1.329	0.977
rs2144908	0.148	0.204	1.467	1.143 – 1.882	0.003*
rs6031550	0.229	0.204	0.865	0.690 – 1.084	0.209
rs6031551	0.229	0.208	0.882	0.701 – 1.109	0.282
rs6031552	0.225	0.193	0.823	0.650 – 1.042	0.106
rs6130716	0.336	0.320	0.929	0.756 – 1.140	0.479
rs6031558	0.324	0.303	0.910	0.741 – 1.119	0.371
rs6130608	0.264	0.256	0.961	0.771 – 1.197	0.721
rs2425637	0.464	0.469	1.019	0.843 – 1.232	0.845
rs2425639	0.471	0.461	0.957	0.789 – 1.161	0.659
rs3212172	0.141	0.178	1.300	1.007 – 1.680	0.044*
rs1800963	0.392	0.441	1.218	1.002 – 1.480	0.048*
rs2071197	0.093	0.097	1.042	0.757 – 1.434	0.802
rs736824	0.389	0.395	1.027	0.841 – 1.255	0.791
rs745975	0.231	0.239	1.045	0.829 – 1.317	0.710
rs3212183	0.474	0.461	0.951	0.788 – 1.148	0.600
rs1885088	0.229	0.234	1.025	0.817 – 1.286	0.828
rs1800961	0.026	0.027	1.043	0.573 – 1.898	0.890
rs3212195	0.207	0.237	1.184	0.924 – 1.517	0.181
rs3212198	0.408	0.396	0.950	0.776 – 1.162	0.617
rs3818247	0.349	0.354	1.019	0.834 – 1.245	0.851

Distribution of the genotyped SNPs minor allele frequencies. Allelic association for individual SNPs was carried out using logistic regression by fitting an additive model. CI=confidence interval; MAF=minor allele frequency; CD= Crohn’s disease.

^*P <0.05