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. Author manuscript; available in PMC: 2017 Jul 1.
Published in final edited form as: J Allergy Clin Immunol. 2016 Mar 3;138(1):123–129.e2. doi: 10.1016/j.jaci.2015.11.037

Figure 5. The pulmonary veins are an important mediator of airway inflammation.

Figure 5

(A) H&E-stained airways of both WT and αT-cat KO mice exposed to HDM, showing inflammation from the PV in WT mice. (B) Percent PAS-positive staining as a function of distance to the nearest PV. Each of the 21 data points in the regression analysis represents a single PAS-positive airway from HDM-treated WT mice, one tissue section each, from Figure 1 (n=5 mice). (C) Measurement of raw intensity of αE-cat in PV junctions of WT (n=50) and KO (n=98) mice exposed to HDM, normalized to WT. AW=airway, PA=Pulmonary artery, PV=Pulmonary vein. *p<0.05, Student’s t-test. Error bars=S.E.M.