Fig. 4.

Panel A: Simulated sedimentation profiles of a population of species with uniform distribution between 1,300 S and 1,700 S, assuming a partial specific volume of 0.73 ml/g and a frictional ratio of 1.2, sedimenting at 8,000 rpm, shown in 300 sec intervals from 420 sec to 1,020 sec (circles). The solid line is the best-fit boundary of a ls-g*(s) model, neglecting diffusion. Panel B: Residuals of the fit. Panel C: The best-fit ls-g*(s) distribution (bold line) and the distribution underlying the simulation (thin dotted line).