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. Author manuscript; available in PMC: 2017 Jul 1.
Published in final edited form as: Mol Ecol. 2016 Jun 6;25(13):3081–3100. doi: 10.1111/mec.13671

Table 3.

Selected biological processes enriched for outliers of each statistic are given. For each statistic, biological process GO categories represented in at least five outlier regions were identified. Of those with raw permutation P value below 0.01, the categories with the highest proportion of outliers are listed here. Highly similar GO categories were omitted to minimize redundancy.

Windows χMD χMD XP-EHH XP-EHH FST FST
GO ID Description w/ Genes Outliers P Outliers P Outliers P
χMD Enrichment
43524 negative regulation of neuron apoptotis 13 7 0.001 4 0.103 4 0.054
32006 regulation of TOR signaling cascade 11 5 0.008 5 0.006 3 0.095
48190 wing disc dorsal/ventral pattern formation 46 16 0.004 13 0.031 9 0.159
9582 detection of abiotic stimulus 55 18 0.002 17 0.002 13 0.016
45448 mitotic cell cycle, embryonic 28 9 0.004 1 0.977 6 0.050
7602 phototransduction 43 13 0.007 13 0.004 11 0.007
31124 mRNA 3'-end processing 30 9 0.002 5 0.201 3 0.551
6289 nucleotide-excision repair 24 7 0.003 6 0.013 4 0.102
6401 RNA catabolic process 32 8 0.009 7 0.026 3 0.507
22613 ribonucleoprotein complex biogenesis 35 8 0.006 7 0.021 7 0.011
42451 purine nucleoside biosynthetic process 44 10 0.007 6 0.209 10 0.002
6260 DNA replication 66 14 0.004 7 0.466 13 0.002
70647 prot. modif. by small prot. conjug./removal 91 19 0.002 17 0.009 16 0.004
8340 determination of adult lifespan 145 30 0.001 19 0.261 26 0.001
6310 DNA recombination 56 11 0.006 9 0.039 8 0.049
XP-EHH Enrichment
32006 regulation of TOR signaling cascade 11 5 0.008 5 0.006 3 0.095
6917 induction of apoptosis 20 5 0.251 8 0.007 6 0.029
71453 cellular response to oxygen levels 28 7 0.130 10 0.003 7 0.044
6816 calcium ion transport 31 9 0.050 11 0.003 10 0.002
7369 gastrulation 31 8 0.133 11 0.004 10 0.003
46662 regulation of oviposition 18 1 0.909 6 0.009 3 0.238
9581 detection of external stimulus 60 19 0.002 19 0.001 15 0.005
10942 positive regulation of cell death 53 9 0.619 16 0.006 13 0.013
8344 adult locomotory behavior 60 16 0.018 16 0.010 11 0.098
7291 sperm individualization 45 9 0.047 11 0.005 10 0.004
52548 regulation of endopeptidase activity 47 9 0.051 11 0.005 10 0.004
50906 detect. stimulus involved in sensory percept. 84 14 0.167 19 0.003 19 <0.001
9416 response to light stimulus 119 25 0.014 26 0.003 25 <0.001
7349 cellularization 94 16 0.064 20 0.002 18 0.002
43900 regulation of multi-organism process 81 9 0.689 17 0.009 17 0.001
FST Enrichment
35072 ecdysone-mediated induction of salivary gland cell autophagic cell death 11 3 0.622 5 0.083 6 0.005
7157 heterophilic cell-cell adhesion 25 10 0.098 11 0.019 13 <0.001
61057 peptidoglycan recog. prot. signal. pathway 10 2 0.228 3 0.052 5 <0.001
35073 pupariation 11 2 0.386 1 0.740 5 0.002
51260 protein homooligomerization 17 6 0.034 5 0.090 7 0.002
35303 regulation of dephosphorylation 13 4 0.033 4 0.029 5 0.002
6963 pos. regul. of antibact. peptide biosynthesis 21 3 0.612 3 0.565 8 0.001
43279 response to alkaloid 22 2 0.859 5 0.165 8 0.002
12502 induction of programmed cell death 31 7 0.318 11 0.006 11 0.001
43523 regulation of neuron apoptotic process 17 8 0.001 5 0.064 6 0.007
10950 pos. regulation of endopeptidase activity 17 5 0.045 5 0.039 6 0.004
45088 regulation of innate immune response 20 3 0.468 2 0.712 7 0.002
71897 DNA biosynthetic process 27 6 0.036 5 0.099 9 <0.001
50911 detection of chemical stimulus involved in sensory perception of smell 40 5 0.552 10 0.011 13 <0.001
16337 cell-cell adhesion 80 25 0.083 25 0.028 26 <0.001