Table 3.
Selected biological processes enriched for outliers of each statistic are given. For each statistic, biological process GO categories represented in at least five outlier regions were identified. Of those with raw permutation P value below 0.01, the categories with the highest proportion of outliers are listed here. Highly similar GO categories were omitted to minimize redundancy.
Windows | χMD | χMD | XP-EHH | XP-EHH | FST | FST | ||
---|---|---|---|---|---|---|---|---|
GO ID | Description | w/ Genes | Outliers | P | Outliers | P | Outliers | P |
χMD Enrichment | ||||||||
43524 | negative regulation of neuron apoptotis | 13 | 7 | 0.001 | 4 | 0.103 | 4 | 0.054 |
32006 | regulation of TOR signaling cascade | 11 | 5 | 0.008 | 5 | 0.006 | 3 | 0.095 |
48190 | wing disc dorsal/ventral pattern formation | 46 | 16 | 0.004 | 13 | 0.031 | 9 | 0.159 |
9582 | detection of abiotic stimulus | 55 | 18 | 0.002 | 17 | 0.002 | 13 | 0.016 |
45448 | mitotic cell cycle, embryonic | 28 | 9 | 0.004 | 1 | 0.977 | 6 | 0.050 |
7602 | phototransduction | 43 | 13 | 0.007 | 13 | 0.004 | 11 | 0.007 |
31124 | mRNA 3'-end processing | 30 | 9 | 0.002 | 5 | 0.201 | 3 | 0.551 |
6289 | nucleotide-excision repair | 24 | 7 | 0.003 | 6 | 0.013 | 4 | 0.102 |
6401 | RNA catabolic process | 32 | 8 | 0.009 | 7 | 0.026 | 3 | 0.507 |
22613 | ribonucleoprotein complex biogenesis | 35 | 8 | 0.006 | 7 | 0.021 | 7 | 0.011 |
42451 | purine nucleoside biosynthetic process | 44 | 10 | 0.007 | 6 | 0.209 | 10 | 0.002 |
6260 | DNA replication | 66 | 14 | 0.004 | 7 | 0.466 | 13 | 0.002 |
70647 | prot. modif. by small prot. conjug./removal | 91 | 19 | 0.002 | 17 | 0.009 | 16 | 0.004 |
8340 | determination of adult lifespan | 145 | 30 | 0.001 | 19 | 0.261 | 26 | 0.001 |
6310 | DNA recombination | 56 | 11 | 0.006 | 9 | 0.039 | 8 | 0.049 |
XP-EHH Enrichment | ||||||||
32006 | regulation of TOR signaling cascade | 11 | 5 | 0.008 | 5 | 0.006 | 3 | 0.095 |
6917 | induction of apoptosis | 20 | 5 | 0.251 | 8 | 0.007 | 6 | 0.029 |
71453 | cellular response to oxygen levels | 28 | 7 | 0.130 | 10 | 0.003 | 7 | 0.044 |
6816 | calcium ion transport | 31 | 9 | 0.050 | 11 | 0.003 | 10 | 0.002 |
7369 | gastrulation | 31 | 8 | 0.133 | 11 | 0.004 | 10 | 0.003 |
46662 | regulation of oviposition | 18 | 1 | 0.909 | 6 | 0.009 | 3 | 0.238 |
9581 | detection of external stimulus | 60 | 19 | 0.002 | 19 | 0.001 | 15 | 0.005 |
10942 | positive regulation of cell death | 53 | 9 | 0.619 | 16 | 0.006 | 13 | 0.013 |
8344 | adult locomotory behavior | 60 | 16 | 0.018 | 16 | 0.010 | 11 | 0.098 |
7291 | sperm individualization | 45 | 9 | 0.047 | 11 | 0.005 | 10 | 0.004 |
52548 | regulation of endopeptidase activity | 47 | 9 | 0.051 | 11 | 0.005 | 10 | 0.004 |
50906 | detect. stimulus involved in sensory percept. | 84 | 14 | 0.167 | 19 | 0.003 | 19 | <0.001 |
9416 | response to light stimulus | 119 | 25 | 0.014 | 26 | 0.003 | 25 | <0.001 |
7349 | cellularization | 94 | 16 | 0.064 | 20 | 0.002 | 18 | 0.002 |
43900 | regulation of multi-organism process | 81 | 9 | 0.689 | 17 | 0.009 | 17 | 0.001 |
FST Enrichment | ||||||||
35072 | ecdysone-mediated induction of salivary gland cell autophagic cell death | 11 | 3 | 0.622 | 5 | 0.083 | 6 | 0.005 |
7157 | heterophilic cell-cell adhesion | 25 | 10 | 0.098 | 11 | 0.019 | 13 | <0.001 |
61057 | peptidoglycan recog. prot. signal. pathway | 10 | 2 | 0.228 | 3 | 0.052 | 5 | <0.001 |
35073 | pupariation | 11 | 2 | 0.386 | 1 | 0.740 | 5 | 0.002 |
51260 | protein homooligomerization | 17 | 6 | 0.034 | 5 | 0.090 | 7 | 0.002 |
35303 | regulation of dephosphorylation | 13 | 4 | 0.033 | 4 | 0.029 | 5 | 0.002 |
6963 | pos. regul. of antibact. peptide biosynthesis | 21 | 3 | 0.612 | 3 | 0.565 | 8 | 0.001 |
43279 | response to alkaloid | 22 | 2 | 0.859 | 5 | 0.165 | 8 | 0.002 |
12502 | induction of programmed cell death | 31 | 7 | 0.318 | 11 | 0.006 | 11 | 0.001 |
43523 | regulation of neuron apoptotic process | 17 | 8 | 0.001 | 5 | 0.064 | 6 | 0.007 |
10950 | pos. regulation of endopeptidase activity | 17 | 5 | 0.045 | 5 | 0.039 | 6 | 0.004 |
45088 | regulation of innate immune response | 20 | 3 | 0.468 | 2 | 0.712 | 7 | 0.002 |
71897 | DNA biosynthetic process | 27 | 6 | 0.036 | 5 | 0.099 | 9 | <0.001 |
50911 | detection of chemical stimulus involved in sensory perception of smell | 40 | 5 | 0.552 | 10 | 0.011 | 13 | <0.001 |
16337 | cell-cell adhesion | 80 | 25 | 0.083 | 25 | 0.028 | 26 | <0.001 |