Table 2.
Injection protocol of BTX-A
| Author | Type of BTX-A | Source of BTX-A | Amount of BTX-A | Injection sites | No. of injection | Rout of injection | Blinding |
|---|---|---|---|---|---|---|---|
| Zhang et al. [24] | Botulinum toxin type A (BTX-A) | Lanzhou Bioproduction Institute, Lanzhou, China | Group 1:25u Group 2:75u | Dermatome and/or mucosa | 20 | Intradermal and submucosal | Double blind |
| Shehata et al. [26] | Botulinum toxin type A (Botox®) | Not reported | 100u | Trigger zones | 1 | SC | Double blind |
| Wu et al. [23] | BTX-A (100U of Clostridium botulinum type-A neurotoxin complex, 5 mg gelatin, 25 mg dextran, and 25 mg saccharose) | Lanzhou Biological Products Institute, China | 75u | Trigger zones | 15 | Intradermal | Double blind |
| Zúñiga et al. [25] | Onabotulinum toxin A (Botox) | Not reported | 50u | Various sites, 1 cm apart from one another | 1 | SC | Double blind |
SC Subcutaneous