Table 2.
Postoperative nausea and vomiting outcome variables in the first 24 h.
| Aprepitant group | Ondansetron group | P-value | |
|---|---|---|---|
| Number of subjects | 48 | 47 | NA |
| PONV, n (%) | 15 (31) | 17 (36.2) | 0.611 |
| Vomiting, n (%) | 4 (8) | 6 (12.8) | 0.481 |
| Worst vomiting score, median (IQR) | 1.5 (1, 2.5) | 3 (3, 3) | 0.100 |
| Any nausea incidence, n (%) | 15 (31) | 17 (36.2) | 0.611 |
| Significant nausea incidence (A score ≥4 on the VRS), n (%) | 11 (23) | 14 (29.8) | 0.445 |
| Worst nausea score, median (IQR) | 6 (3, 7) | 5 (4, 7) | 0.705 |
| Rescue antiemetics, n (%) | 21 (44) | 25 (53) | 0.357 |
| Postoperative opioid consumption (oral morphine mg), median (IQR) | 54.0 (37.5, 105.0) | 75.0 (30.0, 122.5) | 0.830 |
IQR, interquartile range; %, percentage; n, total number; NA, not applicable; VRS, verbal rating scale.