Table 1.
Variant name | AFNI | FSL | SPM | |
---|---|---|---|---|
Model | First-level regression | Default afni_default | Default fsl_default | Default spm_default |
Second level: 1 sample t-test with ordinary least squares | afni_group_ols | fsl_group_ols | spm_group_ols | |
Second level: 1 sample t-test with weighted least squares | afni_group_wls | fsl_group_wls | spm_group_wls | |
Hemodynamic response function (HRF) | Gamma difference | afni_hrf_gammadiff | fsl_hrf_gammadiff | Default spm_default |
Gamma | Default afni_default | Default fsl_default | NA | |
FIR/TENT Basis Function | afni_hrf_tent | fsl_hrf_fir | spm_hrf_fir | |
Threshold | voxel-wise uncorrected p ≤ 0.001 | Default∗ afni_default | Default∗ fsl_default | Default∗ spm_default |
voxel-wise uncorrected t ≥ 4 | afni_thr_voxelunct4 | NA | spm_thr_voxelunct4 | |
voxel-wise (peak-wise) FWE p ≤ 0.05 | NA | fsl_thr_voxelfwep05 | spm_thr_voxelfwep05 | |
voxel-wise FDR p ≤ 0.05 | afni_thr_voxelfdrp05 | NA | spm_thr_voxelfdrp05 | |
Cluster-wise uncorrected k ≥ 10, cluster-defining threshold p ≤ 0.001 | afni_thr_clustunck10 | NA | spm_thr_clustunck10 | |
Cluster-wise FWE p ≤ 0.05, cluster-defining threshold p ≤ 0.001 | afni_thr_clustfwep05 | fsl_thr_clustfwep05 | spm_thr_clustfwep05 | |
Contrast type | t-contrast | Default∗∗ afni_default | Default∗∗ fsl_default | Default∗∗ spm_default |
f-contrast | afni_con_f | fsl_con_f | spm_con_f | |
Cluster connectivity | 6-Connected: faces | Default afni_default | NA | NA |
18-Connected: faces and edges | afni_clustconn_18 | NA | Default spm_default | |
26-Connected: faces, edges, and corners | afni_clustconn_26 | Default fsl_default | NA | |
Hypothesis type | One-tailed test | afni_alt_onesided | Default fsl_default | Default spm_default |
Two-tailed test | Default afni_default | NA | NA |
Default tests are marked in bold in the table. ∗For group-level analyses, the default threshold is cluster-wise p ≤ 0.05 FWE-corrected. ∗∗For analyses using flexible basis functions to model the HRF the default test is an f-test with an identity matrix of size equal to the number of basis.