Fig. 2.

Locomotor activity of the mice under RF in DD condition. Representative wheel-running activity of the mice under RF as well as free feeding in DD condition for a WT mouse (left) and for a Tg mouse (right). The horizontal scale in the actograms shows ZT. The bar on the right-hand side of each frame denotes the feeding condition with labels. Bars on the top and the bottom of the actograms show the LD 12:12 and DD conditions. In each actogram, the food available time for 4 h is shown in a red rectangle. b A schematic representation of activity in DD of each actogram (left panel WT mouse; right panel Tg mouse). The food available time for 4 h during DD-RF is shown in a red rectangle also in the schematic diagrams. Activity bands are colored in blue. c Periodograms under DD-RF. d Periodograms under DD-FF. In c and d, the left panels show data for the WT mouse and right panels show data for the Tg mouse