Table 5.
Constipation and defecatory dysfunction
| Mechanism | Evaluation | Treatment |
| Slow transit constipation | Radiopaque marker study for colonic transit | High fiber diet, psyllium, proper fluid intake |
| Wireless motility capsule | Adjustment of anticholinergics and dopaminergic agents | |
| Macrogol1 | ||
| Lubiprostone2 | ||
| Dyssynergic defecation | Anorectal manometry | Biofeedback therapy |
| Rectal balloon expulsion | Botulinum neurotoxin injection into the puborectalis | |
| Defecography |
Macrogol-polyethylene glycol (an osmotic laxative);
Lubiprostone-chloride channel activator (increases fluid secretion in the intestine).