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. 2016 Jun 30;6(6):e011714. doi: 10.1136/bmjopen-2016-011714

TableĀ 2.

Summary of the RRs of adverse events in patients with non-small-cell lung cancer

Adverse events Incidence rate (comb group) Incidence rate (mono group) RR 95% CI p Value
Hypertension 84/795 (10.57%) 36/796 (4.52%) 2.19 0.73 to 6.61 0.164
Rash 144/933 (15.43%) 57/934 (6.10%) 2.59 1.40 to 4.79 0.002
Haemorrhage 18/756 (2.38%) 14/757 (1.85%) 1.28 0.65 to 2.52 0.480
Proteinuria 17/505 (3.37%) 9/505 (1.78%) 1.84 0.84 to 4.00 0.126
Diarrhoea 60/545 (11.0%) 20/544 (3.68%) 2.73 1.12 to 6.67 0.027
ILD-like events 4/681 (0.59%) 1/680 (0.15%) 3.00 0.47 to 18.96 0.244

Comb, combination; ILD-like events, interstitial lung disease-like events; mono, monotherapy; RR, risk ratio.