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. 2016 Jun 29;6(6):e011125. doi: 10.1136/bmjopen-2016-011125

Table 2.

Survival estimates from multivariate Cox regression analysis for all-cause mortality

Variable HR (95% CI) χ2 p Value
All-cause mortality (n=670)
 Other CVD 2.07 (1.45 to 2.93) 16.4 <0.0005
 Age 1.03 (1.02 to 1.05) 15.1 <0.0005
 Higher sCRF† 0.40 (0.25 to 0.64) 14.7 <0.0005
 ACE-inhibitor use 1.85 (1.34 to 2.57) 13.8 <0.0005
 Date of CR entry 1.74 (1.25 to 2.41) 10.9 0.001
 Statin use 1.62 (1.18 to 2.22) 8.9 0.003
 Antiplatelet therapy use 0.66 (0.48 to 0.92) 5.9 0.015
 Married/living with partner 0.66 (0.47 to 0.92) 5.9 0.016
 Diuretic use 1.35 (0.97 to 1.87) 3.2 0.075

Univariate predictors: diabetes, physical inactivity, exercise test modality, entry METs, TC/HDL-c ratio, waist circumference, resting heart rate were no longer significant predictors in the multivariate model.

†Entry sCRF level ≥8 METs (men) and ≥7 METs (women).

CVD, cardiovascular disease; CR, cardiac rehabilitation; METs, metabolic equivalents; TC/HDL-c total cholesterol high-density lipoprotein-cholesterol ratio; sCRF, submaximal cardiorespiratory fitness.