Table 3.
Relationship between arterial thrombotic events and mean levels of anticardiolipin isotypes
| aCL measure | Subgroup defined by geometric mean titre over all measures during cohort | No. of thromboses | No. of person-years | Rate (per 1000) | Rate ratios | p Value |
|---|---|---|---|---|---|---|
| IgG | <20 (n=1318) | 154 | 17 333 | 8.9 | 1.0 (Ref. group) | |
| 20+ (n=72) | 14 | 973 | 14.4 | 1.6 (0.9, 2.8) | 0.097 | |
| IgM | <20 (n=1320) | 156 | 17 411 | 9.0 | 1.0 (Ref. group) | |
| 20+ (n=70) | 12 | 894 | 13.4 | 1.5 (0.8, 2.6) | 0.22 | |
| IgA | <20 (n=1379) | 164 | 18 119 | 9.1 | 1.0 (Ref. group) | |
| 20+ (n=11) | 4 | 187 | 21.4 | 2.4 (0.9, 6.4) | 0.088 | |
| RVVT | >45 (n=1208) | 126 | 15 924 | 7.9 | 1.0 (Ref. group) | |
| 45+ (n=78) | 12 | 1096 | 11.0 | 1.3 (0.7, 2.4) | 0.33 |
aCL, anticardiolipin antibody; RVVT, Russell's viper venom time.