Table 2. Number of ADs (aggregation number), micelle radius (nm), core radius (nm), alkyl tail length (nm), packing parameter (P), and micelle surface area (nm2) for the micelles obtained from G2-18C, G2-15C, and G2-13C systems.
| No. ADs | MicelleRadius (nm) | Core Radius (nm) | Tail Length (nm) | Micelle Surface Area (nm2) | Core Volume (nm3) | Headgroup Volume (nm3) | Packing Parameter |
|---|---|---|---|---|---|---|---|
| G2-18C ADs | |||||||
| 13 * | 1.8 | 1.0 | 1.2 | 40.7 | 4.2 | 20.2 | 0.27 |
| 18 | 2.0 | 1.1 | 1.7 | 50.7 | 6.1 | 27.9 | 0.21 |
| 19 (1) * | 2.1 | 1.1 | 1.6 | 53.4 | 6.1 | 30.6 | 0.23 |
| 19 (2) | 2.1 | 1.2 | 1.7 | 53.8 | 6.4 | 30.7 | 0.22 |
| 24 (1) | 2.2 | 1.2 | 1.7 | 60.2 | 7.7 | 36.3 | 0.23 |
| 24 (2) * | 2.2 | 1.2 | 1.7 | 62.3 | 7.7 | 38.5 | 0.24 |
| 26 * | 2.2 | 1.3 | 1.7 | 63.6 | 8.5 | 39.2 | 0.24 |
| 32 | 2.4 | 1.3 | 1.6 | 72.6 | 10.2 | 48.0 | 0.28 |
| Mean | 2.1 | 1.2 | 1.6 | 57.2 | 7.1 | 33.9 | 0.24 |
| G2-15C ADs | |||||||
| 15 * | 2.0 | 1.0 | 1.5 | 47.9 | 4.5 | 26.7 | 0.22 |
| 18 | 2.0 | 1.1 | 1.5 | 52.6 | 5.9 | 30.0 | 0.24 |
| 19(1) * | 2.0 | 1.1 | 1.6 | 52.6 | 5.5 | 30.3 | 0.23 |
| 19(2) * | 2.1 | 1.1 | 1.4 | 52.9 | 5.9 | 30.3 | 0.26 |
| 20 | 2.1 | 1.1 | 1.5 | 53.6 | 6.1 | 30.8 | 0.25 |
| 26 | 2.2 | 1.2 | 1.5 | 63.4 | 8.0 | 39.4 | 0.27 |
| 27 * | 2.3 | 1.3 | 1.5 | 68.4 | 8.8 | 44.4 | 0.28 |
| 31 | 2.4 | 1.3 | 1.5 | 70.4 | 9.1 | 46.5 | 0.29 |
| Mean | 2.1 | 1.2 | 1.5 | 57.7 | 6.7 | 34.8 | 0.26 |
| G2-13C ADs | |||||||
| 12 * | 1.8 | 0.9 | 1.2 | 39.0 | 3.2 | 19.7 | 0.25 |
| 13 * | 1.9 | 0.9 | 1.2 | 43.3 | 3.4 | 23.4 | 0.25 |
| 15 * | 1.9 | 1.0 | 1.1 | 44.6 | 4.3 | 23.7 | 0.31 |
| 19(1) | 2.1 | 1.1 | 1.3 | 53.0 | 5.0 | 31.2 | 0.27 |
| 19(2) | 2.0 | 1.1 | 1.3 | 50.1 | 4.9 | 28.4 | 0.28 |
| 22(1) | 2.1 | 1.1 | 1.2 | 56.6 | 5.5 | 34.5 | 0.29 |
| 22(2) | 2.1 | 1.1 | 1.2 | 56.3 | 5.7 | 33.9 | 0.29 |
| 24 * | 2.2 | 1.1 | 1.2 | 58.1 | 5.6 | 36.1 | 0.3 |
| 29 | 2.4 | 1.3 | 1.2 | 70.8 | 9.6 | 46.4 | 0.35 |
| Mean | 2.0 | 1.1 | 1.2 | 52.4 | 5.3 | 30.8 | 0.29 |
| G1-18C ADs | |||||||
| 28 * | 1.9 | 1.3 | 1.7 | 43.9 | 9.0 | 18.4 | 0.25 |
| 40 * | 2.1 | 1.4 | 1.7 | 53.8 | 12.7 | 24.5 | 0.28 |
| 49 | 2.2 | 1.6 | 1.7 | 62.2 | 15.6 | 30.5 | 0.30 |
| 58 * | 2.3 | 1.6 | 1.6 | 68.9 | 18.6 | 35.2 | 0.34 |
| Mean | 2.1 | 1.5 | 1.7 | 57.2 | 14.0 | 27.1 | 0.29 |
| G0-18C ADs | |||||||
| 18 | 1.4 | 1.1 | 1.5 | 23.6 | 5.5 | 5.3 | 0.24 |
| 26 * | 1.5 | 1.2 | 1.7 | 29.5 | 8.1 | 6.9 | 0.25 |
| 131 * | 3.1 | 2.6 | 1.7 | 77.4 | 48.8 | 63.9 | 0.61 |
| 3.8 | 3.1 | ||||||
| 2.3 | 1.5 | ||||||
| Mean | 2.4 | 1.9 | 1.6 | 43.5 | 20.8 | 25.4 | 0.36 |
Micelles that are effectively bound to siRNA are indicated with an asterisk (*).