Table 3. Pooled diagnostic performances of FFRCT at the per-patient level and at the per-vessel or per-lesion level.
Per-patient level | Per-vessel or per-lesion level | |
---|---|---|
Number of included studies | 5 | 7 |
Number of subjects | 833 | 1377 |
Sensitivity | 0.89 (0.85–0.93)* | 0.84 (0.80–0.87) |
Specificity | 0.76 (0.64–0.84) | 0.76 (0.67–0.83) |
Positive likelihood ratio | 3.68 (2.41–5.61) | 3.51 (2.44–5.03) |
Negative likelihood ratio | 0.14 (0.09–0.21) | 0.21 (0.16–0.27) |
Diagnostic odds ratio | 26.21 (13.14–52.28) | 16.87 (9.41–30.25) |
Diagnostic score | 3.27 (2.58–3.96) | 2.83 (2.24–3.41) |
AUSROC | 0.90 (0.87–0.92) | 0.86 (0.83–0.89) |
Abbreviations: AUSROC: area of summary receiver operating curve.
*Numbers in parentheses are 95% confidence intervals.