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. 2016 Jul 5;6:29475. doi: 10.1038/srep29475

Figure 4. Alpha-synuclein (Snca) is a module 23 hub gene.

Figure 4

(A) We observed a positive correlation (rs = −0.80, P = 4.3 × 10−31) between Kme and the magnitude of differential expression between OVX and SHAM (FDR) across the three inbred strains. The diagonal line represents the smoothed best fit. Genes to the left of the vertical dashed line were differentially expressed at an FDR < 10%. (B) Snca expression is lower in all three inbred strains (P = 9.0 × 10−3). (C) Snca is highly expressed in bone marrow (in red) and expressed in differentiating osteoblasts (in blue).