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. 2016 Jul 5;6:29475. doi: 10.1038/srep29475

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Copyright © 2016, Macmillan Publishers Limited

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Body weight (A), total volume (TV) (B), bone volume (BV) (C), bone volume fraction (BV/TV) (D), trabecular number (Tb.N) (E), trabecular thickness (Tb.Th) (F) and trabecular separation (Tb.Sp) of the L4 vertebrae in OVX and SHAM mice from both Snca genotypes (Snca^−/− and Snca^+/+) (N = 10 for both OVX groups, N = 9 for Snca^+/+ SHAM and N = 6 for Snca^+/+ OVX). Percent differences between OVX and SHAM within each genotype are provided. Effect of genotype (Snca^−/− and Snca^+/+), surgery (OVX and SHAM) and interaction between surgery and genotype determined using ANOVA. P geno = P-value for the effect of genotype, P Surg = P-value for the effect of surgery and P Int = P-value for the effect of the interaction between genotype and surgery. P Int ≤ 0.05 indicates a significant difference due to OVX between genotypes. All values are means ± s.e.m.