Table 2. Fasting serum chemistry of Lep^ΔI14/ΔI14 rats at 16 wk of age.

		Triglycerides (mmol/L)	Cholesterol (mmol/L)	HDL (mmol/L)	LDL (mmol/L)
Male	WT	1.17 ± 0.39	0.49 ± 0.15	0.38 ± 0.13	0.30 ± 0.11
	LepΔI14/ΔI14	1.94 ± 0.56*	3.40 ± 2.02* *	0.54 ± 0.12	0.33 ± 0.14
Female	WT	1.27 ± 0.35	0.42 ± 0.15	0.43 ± 0.10	0.27 ± 0.11
	LepΔI14/ΔI14	2.86 ± 0.78* *	4.93 ± 1.65* * *	0.58 ± 0.11*	0.38 ± 0.08

HDL, High-density lipoprotein; LDL, low-density lipoprotein.

Values are means ± SD. (Male: n = 6; Female: n = 6 for WT and n = 5 for Mut).

*P < 0.05 vs. controls. **P < 0.01 vs. controls. ***P < 0.001 vs. controls.