Table 2.

Hazard ratios [95% confidence intervals] and p-values for cortical thickness of AD vulnerable regions in relation to clinical symptom onset, stratified by progression within vs. after 7 years from baseline.

	≤ 7 years from baseline		> 7 years from baseline
	HR	p-value	HR	p-value
Average of AD vulnerable regions	0.50 [0.28, 0.92]	0.03	1.08 [0.74, 1.57]	0.70
Entorhinal cortex	0.79 [0.52, 1.19]	0.26	0.92 [0.63, 1.34]	0.65
Temporal pole	0.61 [0.37, 1.02]	0.058	0.82 [0.51, 1.31]	0.41
Inferior temporal gyrus	0.48 [0.28, 0.81]	0.006	1.30 [0.91, 1.87]	0.16
Middle temporal gyrus	0.42 [0.22, 0.80]	0.008	1.07 [0.72, 1.58]	0.75
Inferior parietal cortex	0.71 [0.43, 1.16]	0.17	1.40 [1.00, 1.96]	0.05
Superior parietal cortex	0.73 [0.48, 1.11]	0.14	1.10 [0.77, 1.59]	0.60
Precuneus	0.58 [0.34, 0.98]	0.04	1.16 [0.81, 1.66]	0.42
Posterior cingulate cortex	0.87 [0.55, 1.37]	0.55	1.15 [0.75, 1.78]	0.52