Table 3.
Comparison of different phenotypes in urbans and tribal subjects.
| Phenotype | Genotype | Urban population(n = 460) | Tribals (n = 100) | p value⁎ |
|---|---|---|---|---|
| Normal metabolizer | CYP2C19*1/CYP2C19*1 | 69 (15%) | 13 (13%) | 0.43 |
| CYP2C19*2/CYP2C19*17 | 62 (13.4%) | 10 (10%) | ||
| CYP2C19*3/CYP2C19*17 | 0 | 01 (1%) | ||
| Intermediate metabolizer | CYP2C19*1/CYP2C19*2 | 167 (36.3%) | 33 (33%) | 0.71 |
| CYP2C19*1/CYP2C19*3 | 01 (0.2%) | 01 (1%) | ||
| Poor metabolizer | CYP2C19*2/CYP2C19*2 | 67 (14.5%) | 28 (28%) | 0.0003 |
| CYP2C19*2/CYP2C19*3 | 03 (0.65%) | 03 (3%) | ||
| Rapid metabolizer | CYP2C19*1/CYP2C19*17 | 76 (16.5%) | 10 (10%) | 0.13 |
| Ultra-rapid metabolizer | CYP2C19*17/CYP2C19*17 | 15 (3.2%) | 01 (1%) | 0.36 |
Table showing categorization of study subjects into different groups based on their genotype (http://www.cypalleles.ki.se/cyp2c19.html, 2016, Goldstein et al., 1997, Furuta et al., 2005).
⁎
p value was obtained using chi square test; p < 0.05 was considered to be significant with two tailed test.