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. 2016 Jun 22;5(6):e60. doi: 10.1038/emi.2016.56

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Inoculation of various EV71 strains and CDVs into BALB/c mice. (A) Kaplan–Meier survival curves of 6-day-old pups inoculated separately with EV71:BS, EV71:TTLLm, EV71:TLLmv, CDV:BS^M-P1 or CDV:BS-VP1^{K98E,E145A,L169F}. Mock-inoculated animals were injected with DMEM (1% FBS). (B) Neutralizing antibody titers in sera collected from inoculated pups that survived until the end of the 28-day observation period. For A, a log-rank (Mantel–Cox) test was used. For B, a t-test was used to compare mean values (n=8). Error bars represent the s.d. **P<0.005. clone-derived virus, CDV.