Table 2.
Functional class | "GATC genes" | all of E. coli's genes | "EcoCyc genes" | "Mitomycin C genes" |
Amino acid metabolism | 2 | 134 | 0 | 5 |
Biosynthesis of cofactors, prosthetic groups, carriers | 2 | 127 | 2 | 1 |
Cell envelope | 2 | 194 | 5 | 10 |
Cellular process | 1 | 102 | 18 | 14 |
Central intermediary metabolism | 4 | 149 | 9 | 15 |
Energy metabolism | 16 | 363 | 6 | 29 |
Fatty acid/Phospholipid metabolism | 8 | 64 | 1 | 4 |
Hypothetical | 11 | 1847 | 12 | 62 |
Nucleotide metabolism | 11 | 120 | 2 | 14 |
Other categories | 3 | 236 | 30 | 15 |
Regulatory functions | 1 | 104 | 12 | 5 |
Replication | 4 | 89 | 14 | 19 |
Transcription | 1 | 47 | 5 | 7 |
Translation | 0 | 150 | 2 | 61 |
Transport/binding protein | 10 | 369 | 28 | 42 |
Total | 76 | 4095 | 146 | 303 |
The table shows the distributions of four groups of genes discussed in this paper, (classified according to the EcoCyc functional classification): the "GATC genes" (genes containing a GATC cluster), all of E. coli's genes, the "EcoCyc genes" (genes induced under various stress conditions according to EcoCyc) and the "Mitomycin C genes" (genes induced by the stress caused by the antibiotic mitomycin C). This table allows the reader to perform the statistical analyses carried out in this paper. The comparison of the distribution of the "GATC genes" with each of the other three groups shows that in all three comparisons three functional classes are overrepresented in the "GATC genes": Energy metabolism, Fatty acid/ Phospholipid metabolism and Nucleotide metabolism. These three classes characterize the GATC regulated network. For an easier interpretation these data are also displayed in the form of histograms in Figures 2, 3 and 4.