Table 1.
GENES | R1881 | R1881 | R1881 | R1881 | R1881 | |||||
---|---|---|---|---|---|---|---|---|---|---|
EP156T | EP156T | EPT3-M1 | EPT3-M1 | LNCaP | LNCaP | 22Rv1 | 22Rv1 | VCaP | VCaP | |
AR | 0 | 0 | 3 | 3 | 64 | 36 | 31 | 26 | 125 | 44 |
KLK3 | 0 | 0 | 0 | 0 | 35 | 799 | 4 | 9 | 5 | 52 |
TMPRSS2 | 4 | 4 | 0 | 0 | 18 | 305 | 4 | 6 | 10 | 63 |
NKX3-1 | 0 | 0 | 4 | 4 | 40 | 139 | 34 | 40 | 171 | 319 |
KLK2 | 0 | 0 | 0 | 0 | 5 | 169 | 5 | 12 | 447 | 1010 |
FKBP5 | 15 | 13 | 40 | 39 | 5 | 331 | 30 | 254 | 7 | 181 |
TP63 | 45 | 40 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
MYC | 37 | 35 | 21 | 20 | 34 | 8 | 38 | 37 | 91 | 19 |
EP156T, EPT3-M1 and LNCaP cells were treated with 10 nM R1881 for 48 hours and 22Rv1 and VCaP cells with 1 nM R1881 for 24 hours. Values are in fragments per kilobase of exon per million reads mapped (fpkm) and rounded to the nearest integer