Table 2.
Parameters 1 year post-PEA according to non-residual and residual PH
| Non-residual PH | Residual PH | p-value | |
|---|---|---|---|
| Patients, n (%) | 16 (43.2) | 21 (56.8) | |
| WHO functional class, (%) | a | 0.002 | |
| I | 46.2 | None | |
| II | 53.8 | 57.1 | |
| III | None | 42.9 | |
| IV | None | None | |
| 6MWT | |||
| 6MWD (m) | 487.6 ± 72.1 | 432.4 ± 148.9 | 0.26 |
| Rest SpO2 (%) | 97 ± 1.9 | 94.8 ± 3.1 | 0.05 |
| Peak SpO2 (%) | 94.3 ± 4.4 | 90.8 ± 4.1 | 0.05 |
| Δ SpO2 (%) | −2.7 ± 3.8 | −3.9 ± 4.4 | 0.47 |
| Rest HR (beatsamin-1) | 83.9 ± 15.1 | 83.2 ± 13.9 | 0.9 |
| Peak HR (beatsamin-1) | 101.6 ± 15.2 | 111.5 ± 17.6 | 0.2 |
| Δ HR (beatsamin-1) | 17.8 ± 6.3 | 28.3 ± 14.4 | 0.06 |
| HRR (%) | 24.3 ± 11.5 | 28.3 ± 14.4 | 0.05 |
| Δ Borg | 1.7 ± 1.9 | 3.9 ± 2.4 | 0.02 |
| Supplemental Oxygen (n, %) | 1 (6.3) | 2 (9.5) | - |
| Lung function | |||
| FEV1 (% pred.) | 93.9 ± 12.8 | 83.9 ± 10.6 | 0.02 |
| FEV1/FVC (% pred.) | 95.8 ± 13.9 | 86.7 ± 9.2 | 0.03 |
| TLC (% pred.) | 104.2 ± 15.2 | 105.2 ± 18.3 | 0.87 |
| VC (% pred.) | 96.8 ± 14.0 | 92.1 ± 11.6 | 0.3 |
| RHC | |||
| mPAP (mm Hg) | 19.7 ± 3.2 | 36 ± 7.5 | 0.001 |
| RAP (mm Hg) | 5.5 ± 2.4 | 8.7 ± 5.1 | 0.04 |
| PVR (dyneas/cm5) | 218.3 ± 280.9 | 415.9 ± 163.7 | 0.012 |
| CI (l/min/m2) | 2.9 ± 0.4 | 2.6 ± 0.6 | 0.09 |
| PAWP (mm Hg) | 8.9 ± 3.8 | 12.2 ± 4.7 | 0.037 |
| Echocardiography | |||
| TAPSE (mm) | 18.3 ± 2.7 | 16.7 ± 3.6 | 0.2 |
| PASP (mm Hg) | 50.6 ± 29.2 | 59.5 ± 21.9 | 0.5 |
| CPETb | |||
| Peak VO2 (ml/min/kg) | 15.2 ± 4.5 | 13.3 ± 3.9 | 0.36 |
| Rest VD/VT | 30.3 ± 5.1 | 35.3 ± 6.4 | 0.35 |
| Peak VD/VT | 27.7 ± 6.1 | 41.2 ± 12.1 | 0.13 |
| Rest VD, L | 0.22 ± 0.07 | 0.37 ± 0.09 | 0.09 |
| Peak VD, L | 0.63 ± 0.1 | 0.78 ± 0.26 | 0.39 |
| Rest SpO2 (%) | 95.1 ± 1.3 | 93.7 ± 1.8 | 0.10 |
| Peak SpO2 (%) | 89.1 ± 7.3 | 89.6 ± 4.6 | 0.86 |
| Δ SpO2 (%) | −5.2 ± 5.4 | −3.6 ± 3.3 | 0.69 |
| Rest HR (beatsamin-1) | 76.1 ± 12.4 | 69.9 ± 11.7 | 0.15 |
| Peak HR (beatsamin-1) | 125.3 ± 22.4 | 116.6 ± 19.9 | 0.25 |
| Δ HR (beatsamin-1) | 49.2 ± 19.3 | 46.7 ± 19.9 | 0.72 |
| HRR (%) | 55.1 ± 21.1 | 54.3 ± 21.8 | 0.92 |
| Jamieson-Type, (%) | a | 0.15 | |
| I | 14.2 | 46.7 | |
| II | 42.9 | 20 | |
| III | 42.9 | 33.3 | |
| Laboratory | |||
| NT-proBNP (pg/ml) | 175.0 [56–259] | 389.0 [95–703] | 0.18 |
Values represent mean ± SD or median [IQR]. a = Pearson Chi-Square test, b n = 34. For abbreviations see Table 1