Table 2.
Risks of psychiatric disorders, suicide attempt and suicide in siblings of individuals with EDS (EDS siblings), compared with matched siblings to individuals without EDS (comparison siblings)
| EDS siblings (n = 1,722) | Comparison siblings (n = 16,920) | |||
|---|---|---|---|---|
| n (%) | n (%) | RR (95 % CI) | RRa (95 % CI) | |
| Autism spectrum disorder | 10 (0.6) | 56 (0.4) | 1.8 (0.9–3.4) | 1.7 (0.9–3.2) |
| Bipolar disorder | 7 (0.5) | 69 (0.4) | 1.0 (0.5–2.0) | 0.9 (0.4–2–0) |
| ADHD | 26 (1.5) | 123 (0.7) | 2.1 (1.4–3.3) | 2.1 (1.4–3.3) |
| Depression | 72 (4.2) | 492 (2.9) | 1.5 (1.1–1.8) | 1.4 (1.1–1.8) |
| Suicide attempt | 66 (3.8) | 364 (2.1) | 1.8 (1.4–2.3) | 1.8 (1.4–2.3) |
| Suicide | 10 (0.6) | 44 (0.3) | 2.1 (1.2–3.9) | 2.3 (1.3–4.1) |
| Schizophrenia | 7 (0.4) | 54 (0.3) | 1.3 (0.6–2.7) | 1.4 (0.6–3.1) |
Associations are expressed as risk ratios (RR) and 95 % confidence intervals (95 % CIs) from conditional logistic regression
Note: statistically significant RR are bolded. RRa, risk ratios restricted to individuals born in Sweden