Fig. 1.
Two group comparison for the differentiation of no to moderate (F0–F2) and severe (F3, F4) fibrosis stages. Upper and lower bounds of boxes represent the first and third quartile per group, whiskers extend to the most extreme data point which is no more than 1.5 times the interquartile range from the box. Circles represent individual data points. Solid grey boxes represent the summarized two experimental groups tested for statistical significance by Student’s t test (p value < 2.2·10−16), while the white boxes represent the individual fibrosis stages F0–F4 (Desmet-Scheuer score). For reasons of clarity, the box plots for the combined groups (0–2 vs. 3–4) do not display the individual data points as the box plots for the individual groups