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. 2016 Jul 5;7:253. doi: 10.3389/fphys.2016.00253

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Copyright © 2016 Pires, dos Anjos, Covolan, Pinheiro, St Clair Gibson, Noakes, Magalhães and Ugrinowitsch.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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(A–C) Cerebral oxygenation (COX) measured at the prefrontal cortex (PFC) during maximal controlled-pace (MIT) and self-paced (TT_4km) exercise. Symbols indicate exercise mode (†) and time (‡) main effects, as well as time-by-exercise mode interaction effects (^*). Panels (A–C) depict Δ[O₂Hb], Δ[HHb], and Δ[THb].