Table 7.
Metabolic differences in plasma of experimental vs control animals. Fold change is expressed as Experimental/Control. N=9 animals per group
| Super Pathway | Sub Pathway | Biochemical Name | Fold changes | p-value |
|---|---|---|---|---|
| Amino Acid | Polyamine Metabolism | 5-methylthioadenosine (MTA) | 0.78 | 0.0063 |
| Phenylalanine and Tyrosine Metabolism | o-cresol sulfate | 0.58 | 0.0197 | |
| Methionine, Cysteine, SAM and Taurine Metabolism | methionine sulfone | 0.66 | 0.0288 | |
| Urea cycle; Arginine and Proline Metabolism | citrulline | 0.86 | 0.0364 | |
| Glutamate Metabolism | S-1-pyrroline-5-carboxylate | 0.8 | 0.0391 | |
| Carbohydrate | Glycolysis, Gluconeogenesis, and Pyruvate Metabolism | 1,5-anhydroglucitol (1,5-AG) | 1.22 | 0.0059 |
| Advanced Glycation End-product | N6-carboxymethyllysine | 0.65 | 0.0107 | |
| Cofactors and Vitamins | Thiamine Metabolism | thiamin monophosphate | 1.32 | 0.0042 |
| Lipid | Lysolipid | 1-linoleoyl-GPE (18:2) | 0.64 | 0.001 |
| 1-palmitoyl-GPE (16:0) | 0.85 | 0.0076 | ||
| 1-arachidonoyl-GPE (20:4) | 0.69 | 0.0089 | ||
| 1-palmitoyl-GPI (16:0) | 0.65 | 0.0114 | ||
| 1-stearoyl-GPI (18:0) | 0.7 | 0.015 | ||
| 1-oleoyl-GPE (18:1) | 0.75 | 0.0179 | ||
| 1-linoleoyl-GPI (18:2) | 0.66 | 0.0228 | ||
| 2-palmitoleoyl-GPC (16:1) | 0.8 | 0.0345 | ||
| 1-stearoyl-GPE (18:0) | 0.8 | 0.044 | ||
| Lysoplasmalogen | 1-(1-enyl-palmitoyl)-GPE (P-16:0) | 0.81 | 0.0238 | |
| 1-(1-enyl-stearoyl)-GPE (P-18:0) | 0.76 | 0.0061 | ||
| 1-(1-enyl-oleoyl)-GPE (P-18:1) | 0.63 | 0.01 | ||
| Sterol | campesterol | 0.75 | 0.0415 | |
| Xenobiotics | Food Component/Plant | 4-ethylphenol glucuronide | 3.95 | 0.0098 |
| indoleacrylate | 0.39 | 0.0246 | ||
| Benzoate Metabolism | 4-ethylphenylsulfate | 3.06 | 0.0336 |