Table 1.
Demographic and Clinical Characteristics by LVEF category
| Characteristic | LVEF (%) | |||
|---|---|---|---|---|
| <50 (n=164) |
50-55 (n=363) |
>55 (n=9,743) |
p value | |
| Age, y | 61 (13) | 57 (13) | 60 (12) | <0.0001 |
| Male, n (%) | 128 (78) | 216 (60) | 4078 (42) | <0.0001 |
| BMI, kg/m2 | 26.9 (4.7) | 27.6 (4.5) | 27.0 (4.8) | 0.07 |
| Prevalent CVD, n (%) | 74 (45) | 62 (17) | 1086 (11) | <0.0001 |
| Prevalent MI, n (%) | 45 (27) | 23 (6) | 262 (3) | <0.0001 |
| SBP, mm Hg | 132 (19) | 133 (20) | 130 (20) | 0.01 |
| DBP, mm Hg | 77 (11) | 79 (10) | 76 (10) | <0.0001 |
| Hypertension, n (%) | 96 (59) | 174 (48) | 4594 (47) | 0.015 |
| Hypertension treatment, n (%) | 68 (41) | 87 (24) | 3066 (32) | 0.0002 |
| Diuretic use, n (%) | 23 (14) | 49 (14) | 1460 (15) | 0.69 |
| Aspirin use, n (%)* | 64 (40) | 110 (32) | 2537 (30) | 0.026 |
| Lipid-lowering therapy, n (%) | 36 (22) | 40 (11) | 1544 (16) | 0.0042 |
| Diabetes, n (%) | 28 (17) | 42 (12) | 739 (8) | <0.0001 |
| Smoking, n (%) | 34 (21) | 74 (20) | 1588 (16) | 0.048 |
| LVEDD, cm | 5.4 (0.8) | 5.0 (0.5) | 4.8 (0.5) | <0.0001 |
| BNP | 54.3 (39.0) | 33.1 (42.7) | 15.0 (20.0) | <0.0001 |
BMI = body mass index. BNP= Brain natriuretic peptide. CVD = cardiovascular disease (coronary artery disease, myocardial infarction, angina, CVA, or TIA). DBP = Diastolic blood pressure. LVEDD = left ventricular end-diastolic dimension. LVEF = left ventricular ejection fraction. MI = myocardial infarction. SBP = Systolic blood pressure.
Measures are reported as mean (SD) for continuous variables and n (% prevalence) for categorical variables.
*
Data on aspirin use was not available for Original Cohort examination 16.