Table 4.

Hazards Ratios for Outcomes by Categorical and Continuous LVEF

LVEF (%)	Model 1 HR (95% CI)	p value	Model 2 HR (95% CI)	p value
HF or Death (n=1,255 events)
<50	2.35 (1.79, 3.08)	<0.0001	2.01(1.53, 2.64)	<0.0001
50-55	1.46 (1.12, 1.91)	0.0048	1.37 (1.05,1.80)	0.023
>55	Referent		Referent
Continuous*	1.14 (1.10, 1.18)	<0.0001	1.12 (1.07, 1.16)	<0.0001
HF (n=355 events)
<50	3.38 (2.23, 5.12)	<0.0001	2.84 (1.87, 4.31)	<0.0001
50-55	2.25 (1.48, 3.42)	0.0002	2.15 (1.41, 3.28)	0.0004
>55	Referent		Referent
Continuous*	1.26 (1.18, 1.35)	<0.0001	1.23 (1.15, 1.32)	<0.0001

Analyses stratified by Cohort and by prevalent MI. HF = heart failure. HR = hazard ratio. LVEF = left ventricular ejection fraction.

^*HR per 5% decline in LVEF

Model 1: Adjusted for age and sex

Model 2: Adjusted for age, sex, body mass index, baseline cardiovascular disease, smoking, diabetes, systolic blood pressure, history of hypertension treatment