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. 2016 Jun 13;113(26):E3764–E3772. doi: 10.1073/pnas.1521749113

Table S1.

Strains, number, and age of mice used in various analyses and assays in this study

Assessment n Age, postnatal days
ERG analysis of retinal function
 WT 11 35
Rd10-non 6 35
Rd10+PTZ 9 35
Rd10/Sig1R−/− 5 35
Rd10/Sig1R−/−+PTZ 3 35
OCT analysis of retinal structure (in vivo imaging)
 WT 5 21
Rd10-non 7 21
Rd10+PTZ 9 21
Rd10/Sig1R−/− 4 21
Rd10/Sig1R−/−+PT 4 21
 WT 4 28
Rd10-non 4 28
Rd10+PTZ 9 28
 WT 4 35
Rd10-non 5 35
Rd10+PTZ 7 35
 WT 4 42
Rd10-non 10 42
Rd10+PTZ 9 42
Rd10/Sig1R−/− 5 42
Rd10/Sig1R−/−+PTZ) 3 42
Morphometry, immunohistochemistry, TUNEL assay
 WT 15 42
Rd10-non 12 42
Rd10+PTZ 15 42
Rd10/Sig1R−/− 3 42
Rd10/Sig1R−/−+PTZ) 3 42
Assessment of microglia activation and PNA-labeled cones in flatmount preparation
 WT 7 42
Rd10-non 8 42
Rd10+PTZ 10 42
Rd10/Sig1R−/− 6 42
Rd10/Sig1R−/−+ 6 42
Detection of oxidative stress and Nrf2-induced antioxidant genes
 WT 8 42
Rd10-non 10 42
Rd10+PTZ 12 42