Table 3. Rotational relationship of pairs of subunits related by the molecular P (relating the A/B and C/D subunits), Q (relating the A/C and B/D subunits) and R (relating the A/D and B/C subunits) symmetry axes.
The values represent the rotation required for structural superposition of the subunits listed and the departure from linearity of the P, Q and R axes.
| Protein | Rotation A/B (°) | Rotation C/D (°) | Angle between axes (°) | Rotation A/C (°) | Rotation B/D (°) | Angle between axes (°) | Rotation A/D (°) | Rotation B/C (°) | Angle between axes (°) |
|---|---|---|---|---|---|---|---|---|---|
| E. coli thiolase (present study) | 179.7 | 179.6 | 7.13 | 173.4 | 173.3 | 0.84 | 177.4 | 177.4 | 0.32 |
| E. coli thiolase (PDB entry 4wys) | 179.5 | 179.9 | 1.20 | 178.8 | 178.8 | 0.23 | 179.6 | 179.8 | 0.34 |
| Mycobacterium tuberculosis thiolase (P61, ABCD) | 179.1 | 179.8 | 4.42 | 175.7 | 175.4 | 0.29 | 179.4 | 179.3 | 0.57 |
| M. tuberculosis thiolase (P61, EFGH) | 178.8 | 179.9 | 9.10 | 174.9 | 174.4 | 0.59 | 178.6 | 178.6 | 0.75 |
| M. tuberculosis thiolase (P61, JKLM) | 179.1 | 179.9 | 5.84 | 174.4 | 174.0 | 0.43 | 179.6 | 179.7 | 0.56 |
| M. tuberculosis thiolase (C2221) | 179.4 | 179.7 | 0.41 | 178.9 | 178.4 | 0.30 | 179.9 | 179.3 | 0.53 |
| M. tuberculosis thiolase (P21) | 179.4 | 179.9 | 1.89 | 177.8 | 178.5 | 0.28 | 179.8 | 179.9 | 0.55 |
| PDB entry 1dm3 | 179.9 | 179.0 | 1.15 | 178.3 | 179.7 | 0.13 | 178.4 | 178.8 | 0.14 |
| PDB entry 1ulq | 179.3 | 179.7 | 2.56 | 179.1 | 178.3 | 0.85 | 178.1 | 178.2 | 0.54 |
| PDB entry 4c2k | 179.1 | 179.9 | 0.65 | 179.7 | 179.4 | 0.10 | 179.3 | 179.9 | 0.41 |
| PDB entry 4n44 | 179.2 | 179.4 | 0.83 | 179.8 | 178.8 | 0.33 | 179.4 | 179.6 | 0.73 |
| PDB entry 4o99 | 179.9 | 179.7 | 3.40 | 178.9 | 178.6 | 0.08 | 176.9 | 176.8 | 0.27 |
| PDB entry 1ibz | 179.7 | 179.8 | 2.77 | 178.2 | 177.7 | 0.39 | 178.1 | 177.5 | 0.10 |