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. 2015 Jun 30;594(8):2323–2338. doi: 10.1113/JP270710

Figure 2. Sensory nerves limit constriction to perivascular nerve stimulation for Young but not Old MAs .

Figure 2

A, under control conditions, PNS caused similar constrictions in Young MAs (ID rest, 199 ± 6 μm; ID response, 120 ± 10 μm) and Old MAs (ID rest, 183 ± 14 μm; ID response, 113 ± 13 μm). Repeating PNS during capsaicin treatment (10 μm) increased constriction in Young (ID rest, 200 ± 7 μm; ID response, 97 ± 10 μm) but not Old MAs (ID rest, 182 ± 17 μm; ID response, 110 ± 12 μm). B, tetrodotoxin (TTX, 1 μm) blocked constriction to PNS in Young (ID rest, 201 ± 6; ID response, 193 ± 8 μm) and Old MAs (ID rest, 188 ± 17; ID response, 180 ± 15 μm). % Constriction calculated as described in Methods. n = 4 MAs per age group in A and n = 3 MAs per age group in B. *P < 0.05 compared to Control in same age group.