Table 2.
Patient Characteristics (N = 235)
| Characteristic | No. (%) | Median | Range | Interquartile Range |
|---|---|---|---|---|
| Sex | ||||
| Male | 119 (50.6) | |||
| Female | 116 (49.4) | |||
| Race | ||||
| White | 194 (82.6) | |||
| Nonwhite | 41 (17.4) | |||
| Age at RT initiation (years) | 7.2 | 1.0-24.4 | 3.9-12.3 | |
| < 3 | 43 (18.3) | |||
| ≥ 3 | 192 (81.7) | |||
| Age at latest audiogram (years) | 17.0 | 2.1-36.3 | 12.6-21.1 | |
| Time from RT initiation to latest audiogram (years) | 9.0 | 0.8-16.0 | 6.0-11.1 | |
| Post-RT audiograms, No. | 11 | 1-19 | 7-14 | |
| Shunt status | ||||
| Yes | 76 (32.3) | |||
| No | 159 (67.7) | |||
| Surgeries, No. | ||||
| ≤ 1 | 157 (66.8) | |||
| > 1 | 78 (33.2) | |||
| CRD (Gy) | ||||
| Left ear | 29.5 | 0.0-61.7 | 17.0-44.7 | |
| Right ear | 28.8 | 0.0-63.9 | 15.8-42.9 | |
| Tumor location | ||||
| Infratentorial | 86 (36.6) | |||
| Supratentorial | 149 (63.4) | |||
| Histologic diagnosis | ||||
| Ependymoma | 92 (39.1) | |||
| Craniopharyngioma | 73 (31.1) | |||
| Juvenile pilocytic astrocytoma | 37 (15.7) | |||
| Anaplastic astrocytoma | 7 (3.0) | |||
| Optic pathway glioma | 5 (2.1) | |||
| Low-grade astrocytoma | 3 (1.3) | |||
| Ganglioglioma | 3 (1.3) | |||
| Oligodendroglioma | 3 (1.3) | |||
| Glioblastoma multiforme | 2 (0.9) | |||
| Other astroglial tumors* | 10 (4.1) |
Abbreviations: CRD, cochlear radiation dose; RT, radiation therapy.
*
World Health Organization I & II, central neurocytoma, choroid plexus carcinoma, malignant glial neuronal, malignant neurocytoma, neurocytoma, pilomyxoid astrocytoma, and pleomorphic xanthroastrocytoma.