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. 2016 Jan 19;34(10):1057–1064. doi: 10.1200/JCO.2015.63.8171

Table A3.

Overall Survival Estimates for Patients Who Have Undergone Complete Resection for pT1-2N0M0 SCLC, Stratified by Adjuvant Therapy

Adjuvant Therapy Events (deaths), No. Median Survival, 
Months (95% CI) 5-Year Survival, 
% (95% CI)
None 243 of 388 42.1 (34.0 to 51.8) 40.4 (35.2 to 45.5)
Chemotherapy 188 of 354 59.8 (50.8 to 71.1) 50.0 (44.2 to 55.3)
Chemotherapy with radiation to brain 37 of 99 88.9 (72.5 to NA) 67.6 (56.9 to 76.2)
Chemotherapy with radiation to lung 52 of 87 43.8 (28.5 to 78.7) 44.5 (33.6 to 54.9)
 Concurrent chemoradiation 30 of 54 56.8 (31.3 to 91.5) 48.6 (34.3 to 61.5)
 Sequential chemoradiation 21 of 31 29.7 (18.7 to 95.1) 38.2 (21.5 to 54.8)
Radiation to lung 11 of 17 37.5 (19.0 to NA) 47.1 (23.0 to 68.0)

NOTE. Survival data for patients who received adjuvant radiation directed at the brain was not reported as a result of a small sample size (n < 10), in accordance with the National Cancer Data Base Participant Use File Data Use Agreement.

Abbreviations: NA, not available; SCLC, small-cell lung cancer.