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. 2016 May 2;291(25):13257–13270. doi: 10.1074/jbc.M116.718189

FIGURE 2.

FIGURE 2.

Osx-Cre+p53fl/flpRBfl/fl mice develop lung metastases that are detectable at necropsy. Representative images of lung metastasis with low (left panels) and high (right panels) magnification. Lung metastasis in all animals showed the same histopathological features as the primary tumor in the same subject.