FIGURE 7.

Changes to the far-UV CD spectra of MtbAldR were monitored after the addition of respective compounds. A, changes to the far-UV CD spectra monitored after the addition of amino acids. The inset shows the names of the amino acids corresponding to the spectra. The native spectrum corresponds to MtbAldR alone. B and C show far-UV CD spectral changes monitored upon the addition of liothyronine and levothyroxine to MtbAldR. The experiments suggest that MtbAldR exhibits conformational changes upon the addition of the compounds.