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Infusion of [3-13C3]lactate (40 μmol/(kg-min) × 120 min) does not change plasma lactate or TCA cycle intermediate concentrations. A, plasma lactate concentrations before (control) or after a 120-min infusion of C3 lactate. B–D, liver succinate, malate, and aspartate concentrations. In all panels, data are mean ± S.E. of n = 6 per group. N.S., not significant.
