TABLE 5.

Regulators of GTP exchange and protein phosphorylation associated with pHα2 identified using GFP-Trap purification

Gene symbol	Reference	Name	Total peptide
			WT	pHα2
Adrbk1	ARBK1_MOUSE	Adrenergic, β, receptor kinase 1	4	27
Arfgef3	BIG3_MOUSE	ARFGEF family member 3	1	11
Atl1	ATLA1_MOUSE	Atlastin GTPase 1	1	8
Dnm1l	DNM1L_MOUSE	Dynamin 1-like	17	61
Elmo1	ELMO1_MOUSE	Engulfment and cell motility 1	0	6
Gnl1	GNL1_MOUSE	Guanine nucleotide-binding protein-like 1	4	15
Gpsm1	GPSM1_MOUSE	G-protein signaling modulator 1	1	14
Iqsec3	IQEC3_MOUSE	IQ motif and Sec7 domain 3	0	13
Lppr4	LPPR4_MOUSE	Phospholipid phosphatase-related 4	8	67
Mfn2	MFN2_MOUSE	Mitofusin 2	8	32
Nedd4l	NED4L_MOUSE	Neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase	1	7
Ngef	NGEF_MOUSE	Neuronal guanine nucleotide exchange factor	5	37
Opa1	OPA1_MOUSE	Optic atrophy 1 (autosomal dominant)	10	32
Pak7	PAK7_MOUSE	p21 protein (Cdc42/Rac)-activated kinase 7	0	6
Ppm1e	PPM1E_MOUSE	Protein phosphatase, Mg2+/Mn2+-dependent 1E	1	7
Ptprd	PTPRD_MOUSE	Protein-tyrosine phosphatase, receptor type D	6	32
Ptprs	PTPRS_MOUSE	Protein-tyrosine phosphatase, receptor type S	6	29
Rab14	RAB14_MOUSE	RAB14, member RAS oncogene family	8	31
Rab1b	RAB1B_MOUSE	RAB1B, member RAS oncogene family	1	8
Rab33b	RB33B_MOUSE	RAB33B, member RAS oncogene family	2	11
Rab5a	RAB5A_MOUSE	RAB5A, member RAS oncogene family	1	11
Rab5b	RAB5B_MOUSE	RAB5B, member RAS oncogene family	0	7
Rhot1	MIRO1_MOUSE	Ras homolog family member T1, Miro1	4	25
Ric8a	RIC8A_MOUSE	RIC8 guanine nucleotide exchange factor A	2	10
Tbc1d15	TBC15_MOUSE	TBC1 domain family member 15	1	8
Tbc1d17	TBC17_MOUSE	TBC1 domain family member 17	2	9