Liver weights (A), liver triglyceride levels (B), ratio of liver weight to body weight (BW) (C), Oil red-O staining of liver, and the expression of several lipogenic genes in liver (E) of C57BL/6J mice fed a low fat (LF) diet or high fat (HF), butter-rich diets with or without 3% or 5% powdered grapes for 10 weeks. qPCR was conducted to measure mRNA abundance of genes associated with hepatic lipogenesis. Means ± SEM (n=9–10) without a common lowercase letter differ (p<0.05) using one-way ANOVA and Student’s t test. 3S, HF diet containing 3% sugar; 3G, HF diet containing 3% grapes; 5S, HF diet containing 5% sugar; 5G, HF diet containing 5% grapes.