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. Author manuscript; available in PMC: 2016 Jul 5.
Published in final edited form as: Adv Exp Med Biol. 2016;916:335–369. doi: 10.1007/978-3-319-30654-4_15

Fig. 2.

Fig. 2

The Cre/lox-regulated T-ALL model in zebrafish. (a) Schematic of the hsp70:Cre and rag2:loxP-dsRed2-loxP-EGFP-mMyc constructs, (b–g) Overlay of brightfield and fluorescence image of T cells expressing either dsRed2 and/or EGFP-mMyc shows T-LBL/T-ALL development in double transgenic rag2:loxP-dsRed2-loxP-EGFP-mMyc;hsp70:Cre fish, with no (red only) or incomplete (red+green) excision of loxP-dsRed2-loxP cassettes, (a–g). (Republished with permission from Wiley-Blackwell) [88