Fig. 2.

Ammonia imbalance leading to astrocyte swelling that subsequently results in astrocyte-neuron dysfunction. Adapted from Amodio P. Hepatic encephalopathy. In: Lee SS, Moreau R, eds. Cirrhosis: a practical guide to management. Chichester: John Wiley & Sons, 2015, with permission from John Wiley & Sons.¹⁰⁰