Table 1.
Elastic moduli obtained by AFM-based nano-indentation assays
| Cancer type | Cell line | Cell type | Elastic moduli (kPa) | Reference No. |
|---|---|---|---|---|
| Bladder cancer | Hu609 | Non-cancerous | 9.7 ± 3.6 | 29 |
| HCV29 | Non-cancerous | 7.5 ± 3.6 | ||
| Hu456 | Cancerous | 0.3 ± 0.2 | ||
| T24 | Cancerous | 0.8 ± 0.4 | ||
| BC3726 | Cancerous | 1.0 ± 3.6 | ||
| Prostate cancer | BPH | Non-cancerous | 2.8 ± 0.5 | 30 |
| LNCaP | Lowly metastatic | 0.5 ± 0.1 | ||
| PC-3 | Highly metastatic | 1.4 ± 0.2 | ||
| Ovarian cancer | IOSE | Non-cancerous | 2.5 ± 2.0 | 31 |
| HEY | Lowly metastatic | 0.9 ± 0.5 | ||
| HEY48 | Highly metastatic | 0.5 ± 0.2 | ||
| OVCAR-4 | Lowly metastatic | 1.1 ± 0.9 | ||
| OVCAR-3 | Highly metastatic | 0.6 ± 0.2 | ||
| Kidney cancer | RC124 | Non-tumorigenic | 9.38 | 32 |
| A498 | Carcinoma | 7.41 | ||
| ACHN | Adenocarcinoma | 2.48 | ||
| Breast cancer | MCF-10A | Non-cancerous | 1.1 ± 0.5 | 33 |
| MCF-7 | Cancerous | 0.6 ± 0.2 | ||
| Oral cancer | UM1 | Highly metastatic | 3.7 ± 1.0 | 34 |
| UM2 | Lowly metastatic | 6.2 ± 1.4 | ||
| Chondrosarcoma | JJ012 | Highly metastatic | 0.34 | 8 |
| FS090 | Moderately metastatic | 1.27 | ||
| 105KC | Lowly metastatic | 0.79 |
Values are presented as mean ± SD or mean only. AFM, atomic force microscopy.