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. 2016 Feb 24;18(8):1120–1128. doi: 10.1093/neuonc/now023

Fig. 4.

Fig. 4.

Efficacy of local delivery of FGK45 in mouse glioma cell lines. Each group of C57BL6 mice (n = 8) was implanted with GL261 (A), NSCL61 (B), and bRiTs-G3 (C) and treated with CED of 10 µg FGK45 (in 10 µL PBS) on day 5. Control mice received CED of 10 µg IgG (in 10 µL PBS). Survival analysis of GL261 model mice treated with FGK45 or IgG (control) in the GL261 (A), NSCL61 (B), and bRiTs-G3 models (C). Local delivery of FGK45 significantly prolonged survival compared with controls in the NSCL61 (P= .0072) and bRiTs-G3 (P = .0006) models, but the effect was not significant in the GL261 model (P = .1241).