Table 3.
AUROC and diagnostic accuracy for prediction of poor outcome in ALF patients
| AUROC (95% CI) |
P values | Cut-off value | Sensitivity | Specificity | Diagnostic accuracy (%) | |
|---|---|---|---|---|---|---|
| Prothrombin time | 0.698 (0.559–0.836) | 0.0012 | > 35.8 sec | 63 | 80 | 72 |
| sRAGE | 0.770 (0.645–0.896) | <0.0001 | > 3021 pg/mL | 83 | 67 | 75 |
| MELD score | 0.800 (0.559–0.836) | <0.0001 | > 30.02 | 70 | 79 | 75 |
| AST | 0.727 (0.596–0.859) | 0.0006 | > 5768 U/L | 67 | 77 | 72 |
| Creatinine | 0.841 (0.735–0.947) | <0.0001 | > 1.9 mg/dL | 77 | 90 | 84 |
| COMA grade | 0.780 (0.661–0.898) | <0.0001 | > 2 | 87 | 57 | 72 |